1-Piperidinecarboxylic acid, 4-amino-3-methoxy-, 1,1-dimethylethyl ester, (3R,4S)-rel- - Names and Identifiers
1-Piperidinecarboxylic acid, 4-amino-3-methoxy-, 1,1-dimethylethyl ester, (3R,4S)-rel- - Physico-chemical Properties
Molecular Formula | C11H22N2O3
|
Molar Mass | 230.3 |
Density | 1.07±0.1 g/cm3(Predicted) |
Boling Point | 306.2±42.0 °C(Predicted) |
pKa | 9.42±0.40(Predicted) |
Storage Condition | 2-8°C(protect from light) |
1-Piperidinecarboxylic acid, 4-amino-3-methoxy-, 1,1-dimethylethyl ester, (3R,4S)-rel- - Introduction
cis-4-amino-1-BOC-3-methoxypiperidine is an organic compound with the formula C13H21N3O2. It has the following properties:
1. Appearance: cis-4-amino-1-BOC-3-methoxypiperidine is a white to pale yellow crystalline solid.
2. Melting point: Its melting point is about 80-85°C.
3. Solubility: Good solubility in common organic solvents.
4. Stability: The compound is relatively stable under conventional conditions.
The main use of cis-4-amino-1-BOC-3-methoxypiperidine is as an intermediate in organic synthesis. It can be used in the synthesis of protecting groups for high valence compounds, such as amino acids and peptides.
The preparation of the compound can usually be carried out by the following steps:
1. First, piperidine is reacted with dimethylcarbonyl chloride under appropriate reaction conditions to obtain a dimethylcarbonyl derivative of piperidine.
2. Then, the derivative is reacted with the corresponding amine using an appropriate method to obtain cis-4-amino-1-BOC-3-methoxypiperidine.
When using cis-4-amino-1-BOC-3-methoxypiperidine, note the following safety information:
1. Avoid contact with skin and eyes. If in contact, rinse immediately with plenty of water.
2 in the use of the process should avoid inhalation of dust or gas, such as accidentally inhaled, should be quickly transferred to a well-ventilated place.
3. Store away from fire and oxidant.
Last Update:2024-04-10 22:29:15